Cell and gene therapies

From nanoencapsulation systems for personalized medicine, to integrating process analytical technologies (PAT) into bioprocessing devices, we help our clients develop novel cell and gene therapy solutions that change the face of healthcare.

Working collaboratively across applied science, engineering and user-centered design, our cell and gene therapy team is adept at solving the complex and multifaceted challenges in your biotechnology development, from concept to market and beyond.

Bridging the gap between laboratory processes and commercial products

We translate the science behind your technology into a commercially viable device. Our experts work at the interface between science and engineering, optimizing effort, complexity and pay-off to apply automation and analytics that are tailored to your project’s specific needs. With a focus on user-centered design features and robust product functionality, we help you create solutions that achieve your commercial goals.

Reducing timescales and costs

We understand that reducing timescales and costs are key priorities during your development. By pragmatically applying existing technologies where possible, we focus on using experience and analogous applications rather than reinventing the wheel. When custom designs are the best option, our clients will always retain the intellectual property that is produced.

In-house biotechnology expertise

With over 100 applied scientists, designers and engineers, our in-house team hold a diverse and highly relevant skillset to drive your cell and gene therapy solutions forward. Our medical technology experts have experience across a broad range of areas, including Process Analytical Technologies (PAT), bioengineering, molecular biology, nanofabrication, microfluidics, omics, bioprocess engineering, tissue engineering, health economics, GMP expertise, and much more.

Product development from discovery to patient

We provide cell and gene therapy system support from discovery to patient, including localized administration of advanced therapies, laboratory equipment, bioprocessing devices, transport and packaging systems, as well as drug discovery and research tools.

We help our clients across a broad range of cell and gene therapy solutions, including:

Decentralized/Point of Care (PoC) system development
GMP compliant laboratory equipment
Cell or gene therapy manufacturing platforms
Bioreactor design
Clinical trial prototypes for therapy manufacture
Process Analytical Technology (PAT) integration
Cold-chain packaging design
Patient traceability management
Devices for controlling environmentally sensitive material
Aseptic technology development
User-centered design for complex handling
Devices for localized administration: ocular, orthopaedic, intratumoral and more
In vitro organ-on-a-chip technology
Ex vivo tissue / organ perfusion devices
Route to market strategy
Regulatory & compliance gap analysis

Rapid biotechnology development at any stage of your journey

Whether you are looking for a complete cell and gene therapy system development partner or assistance with a specific challenge, our biotechnology experts can help you. Some of the common challenges we support our clients with include:

Route to market planning

In your route to market strategic planning stage, our experts work with stakeholders and key opinion leaders (KOLs) to provide you with an optimized roadmap for your therapy development. We are adept at balancing the confounding interests of regulatory compliance, manufacturing, clinical validation and product development, to help you find the best path to commercialization.

Small batch manufacturing for early clinical trials

If you’re looking for support with small batch manufacture for early clinical trials, we can rapidly produce cost-effective prototypes with high instrumentation, allowing you to identify and control what matters (CQAs & CPPs). Our focus is on ensuring scalability and robust product quality as you progress to later stage clinical trials and production.

Post market support

Once you have successful instruments or products on the market, there are often still many opportunities for improvements to your cell and gene therapy system. Our experts help you identify and integrate the right post market upgrades for your needs, be it integration of PAT into an established manufacturing platform, cost-down analysis, or technical troubleshooting.

Meet one of our cell and gene experts

Kella leads the cell and gene therapy group at Team Consulting, with over 10 years’ experience delivering biotechnology, medical device, diagnostic, and lab equipment projects from concept through to production.

She has a background in polymer chemistry and a PhD in biomaterials engineering from Imperial College London, where she developed tissue engineered cardiac patches for treating heart attacks.

Ask Kella a question

Our passion is helping our clients develop technologies which will ultimately bring an exciting new class of therapies to more patients. This might be through the development of game-changing platforms that drive down the manufacturing costs of cell and gene therapies, or through novel tools which disrupt the traditional approach to research and development, such as microphysiological systems (MPS) or in silico modelling.
Kella Kapnisi, Project Manager, Team Consulting

Revolutionizing nanoencapsulation for personalized medicines

Delivering personalized therapies, one patient at a time. Our client, LEON, challenged us to develop an easy-to-use nano encapsulation system that enables back-to-back aseptic manufacturing for personalized medicine with reliable quality. We helped them develop a benchtop device that is more efficient and cost-effective than conventional systems. The innovative equipment turns what is usually a lengthy process into a 15-minute procedure, thanks to a novel disposable cassette concept.

NANOme® represents a significant advancement in nano encapsulation of medications for personalized medicine and takes us one step closer to our vision of making advanced therapies globally accessible.
LEON Nanodrugs