Case Study

Multi-unit dose disposable dry powder inhaler platform

Aptar Pharma came to Team because of our considerable experience in inhaler design and development, and our in-depth knowledge of the ‘S2’ powder dispersion technology. The client wanted help developing an easy to use, multi-unit dose DPI for the asthma market which could be licensed to pharmaceutical partners. The device needed to carry up to 30 individually packaged doses, incorporate the high performance ‘S2’ powder dispersion technology (licensed from Quadrant ), and be distinctive from competitor devices in terms of its superior safety, intuitive use and simple functionality.

We carried out formative usability research to establish a suitably intuitive user interaction concept, with combined visual and tactile feedback indicating correct use. Preliminary inhalation studies with a range of sub patient groups and naive users were undertaken to define their inhalation profiles and ergonomic capabilities, using the target range of inhalation resistance.  Working with Aptar Pharma we created a strong visual language for the device which would support a simple three-step operation – “open, breathe-in, close” (now trademarked by Aptar Pharma as ‘OBIC Technology’). The visual language also helped define an aesthetic that would appeal to user groups and could be adaptable for potential pharmaceutical partners’ varying brand requirements.

Team worked extensively with Aptar Pharma’s marketing, research & development and production departments throughout. We also had an ongoing working relationship with the primary packaging materials suppliers and production machine designers to ensure a smooth concurrent development.

Through this process we generated a number of patentable solutions and copyrighted designs for the Aptar Pharma. As a result, the Prohaler® is simple, compact, distinctive and manufacturable in high volume. It harnesses unique and highly efficient powder release and dispersion technologies such that the majority of powder reaches the patient’s lung without risk of double dosing. It incorporates a unique breath-triggered dose-opening function and it also features an easy to read dose-counting system that reassuringly, only advances on closure of the device after correct inhalation.

“The Prohaler® is a marvel of the combined application of human factors engineering and design. It’s simple exterior and operation doesn’t provide any clue as to the functionality inside, yet it is naturally intuitive to use for a wide range of asthma and COPD patients. Team did a great job in developing a complete inhaler for us, and we plan to see it entering the market soon via our pharmaceutical partners.”

Pierre Carlotti, VP Marketing & Communication, Aptar Pharma

Please note that the green and white version of the Prohaler (pictured above) was created as part of a colour study to explore visual language and brand differentiation.